Alcohol is the most popular drug of choice at Rhodes. This becomes pretty evident come Thursday night, once the frat parties start up for the weekend. Campus Safety and the RAs are mostly concerned with the well-being of the students, but they aren't in a rush to stop a party. If you're under 21, Campus Safety will just ask you to put your drink down and maybe give you a little lecture about safety, not different from the lecture they'd give their own children. You'll get an alcohol violation if you're being belligerent and out of control, but there's nothing to worry about if you're responsible about drinking. Underage students get violations for having alcohol in their room, too.
As for other drugs, some Rhodes students also enjoy their weed, but it's easy to avoid if that's not your thing. Many students aren't into the drugs and alcohol scene, and that is perfectly fine! No one cares whether you drink and smoke or not, and you don't need alcohol to have fun. There are plenty of other things to do on campus, but you'll have to be willing to accept that there will be drunk people outside on Friday nights. That's the case for any college, though. The important point to note is that Rhodes students are respectful of others' lifestyles and accept that it is a personal choice.