Most of the neighborhoods surrounding Canisius are filled with students. Their occupants are called "resi-muters," since they technically don't live on campus but "commute" by rolling out of bed and walking down the street to get to class. Of course, everybody wants to live in these houses, so good luck getting one of them. The College itself isn't super helpful in finding a place off campus for you to live—other than giving you a list of places and landlords—so count on doing the majority of the legwork yourself. Good apartments are available here and there around the city, but a lot might be out of the average student's budget (which is presumably very minimal, even with a job).
If you find a solid apartment on the other side of the city from Canisius, don't fret. Commutes in the Buffalo area are very quick, smooth, and easy—no matter what direction you're traveling. You'll have no problem getting to class on time if you're already in the city. Nearly all students by their junior year are at least living off the main part of campus, in one of the college townhouses, apartments, or the homes in Hamlin Park.