One of the great things about Hofstra's location is that it's close to a lot of things to do. There is the Roosevelt Field Mall and the Mall at the Source for shopping, two movie theaters that are a short drive away if you want to catch a flick on the weekend, and Jones Beach about 15 minutes away. Right off campus, there's also the Nassau Coliseum that has several concerts and games throughout the year.
However, Hofstra is also located in one of the worst neighborhoods in Nassau County. Hempstead has had many problems with drugs and violence over the years, and even though things are slowly getting better, it's still a pretty dangerous place to be at night or if you're by yourself. If you really must venture off campus, Garden City is a nicer neighborhood with a good amount of stores and restaurants. Or you can always take the LIRR to New York City if you get bored. Just make sure to take it from Mineola because taking it from Hempstead takes longer and the station isn't as nice or safe as Mineola.